Publications

Export 39 results:
2016
Heart E.A., Karandrea S., Liang X., Balke M.E., Beringer P.A., Bobczynski E.M., D. Burgos Z-B, Richardson T., Gray J.P..  2016.  Mechanisms of Doxorubicin Toxicity in Pancreatic β-Cells. Toxicol Sci. 152(2)
Gray J.P., Karandrea S., Burgos D.Z., Jaiswal A.A., Heart E.A..  2016.  NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells. Toxicol Lett. 262
Gray J.P., Burgos D.Z., Yuan T., Seeram N., Rebar R., Follmer R., Heart E.A..  2016.  Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA. Am J Physiol Endocrinol Metab. epub ahead of print
2015
Parmar M.S., Syed I., Gray J.P., Ray S.D..  2015.  Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress-Mediated Hyperglycemia. Curr Neurovasc Res. 12(4)
Gray J.P., Ray S.D..  2015.  Metal Antagonists. Side Effects of Drugs Annual. 37
Goldstone H.M.H., Skomal S., Markie M., Brand A., Gray J.P..  2015.  Publishing returns to the Academy.
2014
Gray J.P, Ray S.D..  2014.  Anticholinergics. Encyclopedia of Toxicology. 1:264-266.
Gray J.P, Hall G.J.  2014.  Benz[a]anthracene. Encyclopedia of Toxicology. 1:413-414.
Gray J.P.  2014.  Benzo(a)pyrene. Encyclopedia of Toxicology. 1:423-428.
Gray J.P, Hall G.J.  2014.  Cotinine. Encyclopedia of Toxicology. 1:1050-1051.
Gray J.P, Shakarjian M.P, Gerecke D.R, Casillas R.P.  2014.  Dermal Toxicity of Sulfur Mustard. Handbook of Toxicology of Chemical Warfare Agents.
Gray J.P., Ray S.D..  2014.  Metal Antagonists. Side Effects of Drugs Annual. 36
2013
Gray J.P, Page E..  2013.  Agents of Bioterrorism: Curriculum and Pedagogy in an Online Masters Course. J Tox EdJ Tox Ed. 1:31-53.
Yang S., Jan Y.H, Gray J.P, Mishin V., Heck D.E, Laskin D.L, Laskin J.D.  2013.  Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells. J Biol ChemJ Biol Chem. 288:19221-37.
2012
Heart E., Palo M., Womack T., Smith P.J, Gray J.P.  2012.  The level of menadione redox-cycling in pancreatic beta-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion. Toxicol Appl PharmacolToxicol Appl Pharmacol. 258:216-25.
Gray J.P, Alavian K.N, Jonas E.A, Heart E.A.  2012.  NAD kinase regulates the size of the NADPH pool and insulin secretion in pancreatic beta-cells. Am J Physiol Endocrinol MetabAm J Physiol Endocrinol Metab. 303:E191-9.
2011
Gray J.P, Eisen T., Cline G.W, Smith P.J, Heart E..  2011.  Plasma membrane electron transport in pancreatic beta-cells is mediated in part by NQO1. Am J Physiol Endocrinol MetabAm J Physiol Endocrinol Metab. 301:E113-21.
Fussell K.C, Udasin R.G, Gray J.P, Mishin V., Smith P.J, Heck D.E, Laskin J.D.  2011.  Redox cycling and increased oxygen utilization contribute to diquat-induced oxidative stress and cytotoxicity in Chinese hamster ovary cells overexpressing NADPH-cytochrome P450 reductase. Free Radic Biol MedFree Radic Biol Med. 50:874-82.
2010
Mishin V., Gray J.P, Heck D.E, Laskin D.L, Laskin J.D.  2010.  Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation by recombinant microsomal enzymes. Free Radic Biol MedFree Radic Biol Med. 48:1485-91.
Wang Y., Gray J.P, Mishin V., Heck D.E, Laskin D.L, Laskin J.D.  2010.  Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity. Mol Cancer TherMol Cancer Ther. 9:1852-63.
Vetrano A.M, Laskin D.L, Archer F., Syed K., Gray J.P, Laskin J.D, Nwebube N., Weinberger B..  2010.  Inflammatory effects of phthalates in neonatal neutrophils. Pediatr ResPediatr Res. 68:134-9.
Gray J.P, Mishin V., Heck D.E, Laskin D.L, Laskin J.D.  2010.  Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species. Toxicol Appl PharmacolToxicol Appl Pharmacol. 247:76-82.
Shakarjian M.P, Heck D.E, Gray J.P, Sinko P.J, Gordon M.K, Casillas R.P, Heindel N.D, Gerecke D.R, Laskin D.L, Laskin J.D.  2010.  Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure. Toxicol SciToxicol Sci. 114:5-19.
Gardner C.R, Gray J.P, Joseph L.B, Cervelli J., Bremer N., Kim Y., Mishin V., Laskin J.D, Laskin D.L.  2010.  Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity. Toxicol Appl PharmacolToxicol Appl Pharmacol. 245:36-46.
Jan Y.H, Heck D.E, Gray J.P, Zheng H., Casillas R.P, Laskin D.L, Laskin J.D.  2010.  Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells. Chem Res ToxicolChem Res Toxicol. 23:1045-53.

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